См. публикацию
AX user sessions hanging following changes to security:
Цитата:
Security cache thrashing can cause a number of different performance issues. A common symptom of this problem is when multiple user sessions becoming unresponsive. This can then lead to high memory usage by the AOSs and increasing numbers of online user sessions, as affected users abandon their hanging session and try to initiate further sessions on the server. New user logons may eventually be blocked, making the system completely inaccessible.
Здесь АОСы упоминаются во множественном числе, так что изменение прав доступа "на лету", видимо, влияет не только на тот АОС, на котором было произведено изменение.